Maneb

MedEd Pesticide lists Maneb as a fungicide in the dithiocarbamate class.

MedEd Pesticide Summarizes Maneb at a Glance

Type

Fungicide

Chemical class

Dithiocarbamate

CAS number

12427-38-2

Formula

C4H6MnN2S4

Molar mass

265.3 g/mol

EU status

Not approved as an active substance in the EU.

US status

Not registered with EPA. All 406 products that contained Maneb are cancelled.

MedEd Pesticide Summarizes Maneb’s Toxicity Records

MedEd Pesticide holds 144 toxicity records for Maneb, from 6 sources. The headline values are below.

Oral LD50 in ratsAcute, swallowed

Lowest reported 3000 mg/kg, median 4875 mg/kg, from 2 records.

Dermal LD50Acute, skin contact

Lowest reported 5000 mg/kg, median 5000 mg/kg, from 1 record.

Lowest NOAELLong term, mammals

5.2 mg/kg-day in primate, 6 months. Source: ToxRefDB.

See all 144 Maneb toxicity records in the explorer. The records come from EPA’s Toxicity Values Database, and the methodology explains their limits.

MedEd Pesticide Reports Maneb’s EU Safety Reference Values

MedEd Pesticide takes these values from the EU, which sets them when it assesses an active substance. They are expressed per kilogram of body weight.

ADIAcceptable daily intake

0.05 mg/kg bw/dayThe amount a person can take in every day over a lifetime without appreciable health risk.

ARfDAcute reference dose

0.2 mg/kg bwThe amount that can be taken in over a short period, such as one meal or one day, without appreciable health risk.

AOELAcceptable operator exposure level

0.03 mg/kg bw/dayThe level of exposure for people who apply the pesticide at which no adverse effect is expected.

MedEd Pesticide Lists Maneb’s EU Hazard Classification

MedEd Pesticide lists the harmonised EU hazard statements for Maneb below.

• H332 Harmful if inhaled
• H400 Very toxic to aquatic life
• H410 Very toxic to aquatic life with long-lasting effects
• H319 Causes serious eye irritation
• H361d Suspected of damaging the unborn child
• H317 May cause an allergic skin reaction

MedEd Pesticide takes EU status, reference values and hazard classification from the EU Pesticides Database. MedEd Pesticide takes US status from EPA’s Pesticide Product Information System (dated 2026-10-13) and chemical identity from PubChem. Retrieved 2026-10-16. Values and approvals change, so check the source for the current entry. See the methodology and the glossary, or compare Maneb with another pesticide.

MedEd Pesticide. (2026). Maneb. https://mededpesticide.org/pesticides/maneb/ (accessed Month Day, Year)